Interactor 1: RENR (O75787)
Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adapter) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) [Cleaved into: Renin receptor N-terminal fragment; Renin receptor C-terminal fragment]
Gene: ATP6AP2

Interactor 2: VA0D2 (Q8N8Y2)
V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2)
Gene: ATP6V0D2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Renin_r~vATP-synt_AC39
Common GO terms GO:0005765 - lysosomal membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016020 - membrane
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 350
Hs

1 350
+ Hs
+ Dm

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Last updated: 15 Jul 2024