HitPredict

Interactor 1: GRAP2 (O75791)
GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona)
Gene: GRAP2

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16636290
Identification Methods	enzyme linked immunosorbent assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~SH3_1, PH~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 1129
+	Hs
		337590 ABL1_HUMAN (4-134): 1.36e-50: 182: 36.23		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		581076 PLCG1_HUMAN (24-328): 1.98e-33: 132: 16.08		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		802771 CRK_HUMAN (46-330): 1.14e-34: 130: 18.87		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		412404 FYN_HUMAN (222-329): 3.95e-22: 98.7: 30.00		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		1285221 SH3K1_HUMAN (273-330): 1.35e-17: 85.7: 31.03		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195785 PLCG1_HUMAN (24-328): 1.98e-33: 132: 16.08		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195788 CRK_HUMAN (46-330): 1.14e-34: 130: 18.87		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195776 FYN_HUMAN (222-329): 3.95e-22: 98.7: 30.00		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195777 YES_HUMAN (198-327): 2.27e-21: 96.4: 21.97		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195796 Q5JPT6_HUMAN (273-330): 1.35e-17: 85.7: 31.03		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		195804 SH3K1_HUMAN (273-330): 1.35e-17: 85.7: 31.03		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		802672 CRK_HUMAN (46-330): 1.14e-34: 130: 18.87		ASAP3_HUMAN (21-913): 7.03e-177: 544: 44.27
+	Hs
		337477 ABL1_HUMAN (4-134): 1.36e-50: 182: 36.23		ACAP1_HUMAN (45-690): 2.77e-153: 477: 21.01
+	Rn
		499164 PLCG1_RAT (24-328): 1.2e-33: 133: 15.79		AGAP2_RAT (379-660): 5.08e-87: 308: 29.02
+	Hs
		411807 LCK_HUMAN (3-136): 1.04e-53: 185: 34.46		ARAP2_HUMAN (162-622): 8.31e-61: 230: 18.97
+	Hs
		802704 CRK_HUMAN (46-330): 1.14e-34: 130: 18.87		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		412284 FYN_HUMAN (222-329): 3.95e-22: 98.7: 30.00		ARAP2_HUMAN (162-622): 8.31e-61: 230: 18.97
+	Hs
		1285175 SH3K1_HUMAN (273-330): 1.35e-17: 85.7: 31.03		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		1262750 SH3K1_HUMAN (273-330): 1.35e-17: 85.7: 31.03		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		63069 CRK_HUMAN (46-330): 1.14e-34: 130: 18.87		RHG42_HUMAN (760-1124): 2.05e-14: 80.3: 12.02