Interactor 1: PR15A (O75807)
Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)
Gene: PPP1R15A

Interactor 2: IF2A (P05198)
Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene: EIF2S1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 12556489, 26100893, 26095357, 29109149
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0016020 - membrane
GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 674
Hs

1 315
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024