Interactor 1: PR15A (O75807)
Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)
Gene: PPP1R15A
Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.954 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12724406, 12016208, 26100893, 15231748, 26095357, 29109149 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, x-ray crystallography, isothermal titration calorimetry, fluorescence polarization spectroscopy, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Metallophos~PP1c_bdg |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008157 - protein phosphatase 1 binding |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
