HitPredict

Interactor 1: EIF3G (O75821)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)
Gene: EIF3G

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 758
+	Hs
		496179 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496957 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496346 ELAV4_HUMAN (229-316): 7.86e-22: 96.4: 27.78		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496937 ELAV2_HUMAN (229-316): 7.55e-22: 96.4: 27.78		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497020 ELAV3_HUMAN (112-316): 1.95e-21: 95.2: 18.84		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496405 TIA1_HUMAN (101-316): 2.31e-16: 81: 20.36		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497082 ELAV1_HUMAN (228-303): 5.65e-15: 76.4: 30.26		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582032 PABP1_RAT (230-320): 3.45e-24: 104: 26.37		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94258 PABP1_RAT (230-320): 3.45e-24: 104: 26.37		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		498054 Q62029_MOUSE (230-320): 6.9e-23: 101: 24.18		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498050 ELAV4_MOUSE (229-316): 7.56e-22: 96.4: 27.78		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		516595 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91