HitPredict

Interactor 1: EIF3G (O75821)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)
Gene: EIF3G

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27381497
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 164
+	Sc
		376921 EIF3G_YEAST (56-318): 1.08e-56: 186: 32.23		PABP_YEAST (2-93): 6.85e-19: 84.2: 20.62
+	Zm
		30171 A0A1D6K4S7_MAIZE (223-320): 5.14e-33: 128: 36.74		A0A1D6M1U3_MAIZE (5-85): 1.01e-30: 115: 42.17
+	Hs
		474017 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		474021 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	At
		286443 ORRM2_ARATH (223-318): 1.91e-30: 114: 32.99		RSZ21_ARATH (10-85): 1.35e-22: 90.5: 51.32
+	Hs
		516466 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		516478 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		266904 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		516425 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		853881 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		516339 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		516495 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		474020 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Hs
		516689 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PABP3_HUMAN (1-91): 6.48e-19: 84.6: 23.71
+	Hs
		516493 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79
+	Mm
		665745 PABP1_MOUSE (230-320): 3.69e-24: 104: 26.37		TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70
+	Hs
		516674 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Hs
		516471 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		TIAR_HUMAN (1-95): 5.6e-18: 81.1: 26.00
+	At
		1323584 ORRM2_ARATH (223-318): 1.91e-30: 114: 32.99		RZ22A_ARATH (11-69): 1.75e-10: 58.5: 59.32