HitPredict

Interactor 1: EIF3G (O75821)
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)
Gene: EIF3G

Interactor 2: PAIP1 (Q9H074)
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)
Gene: PAIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24396066
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006413 - translational initiation
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 479
+	Mm
		1257551 EIF3G_MOUSE (1-320): 5.56e-92: 278: 98.44		PAIP1_MOUSE (85-479): 6.56e-158: 455: 97.22
+	Hs
		474036 PAB4L_HUMAN (136-320): 1.67e-29: 117: 15.14		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		1119144 PAP1L_HUMAN (230-319): 2.16e-24: 105: 26.67		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		1031455 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		516685 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		275855 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		1020328 ELAV2_HUMAN (229-316): 7.55e-22: 96.4: 27.78		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		1288625 PABP5_HUMAN (243-319): 7.67e-17: 82.1: 23.38		PAIP1_HUMAN (1-479): 3.4e-177: 507: 100.00
+	Hs
		203324 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		IF4G3_HUMAN (28-412): 3.45e-89: 299: 18.20
+	Mm
		665767 PABP1_MOUSE (230-320): 3.69e-24: 104: 26.37		PAIP1_MOUSE (85-479): 6.56e-158: 455: 97.22
+	Hs
		69223 EIF3G_HUMAN (1-320): 2.71e-93: 281: 100.00		MI4GD_HUMAN (174-387): 1.71e-42: 151: 19.73
+	Hs
		516476 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		979889 PABP4_HUMAN (230-320): 6.63e-24: 104: 24.18		IF4G1_HUMAN (51-426): 1.82e-97: 323: 20.66
+	Hs
		203335 PABP1_HUMAN (230-320): 3.49e-24: 104: 26.37		IF4G3_HUMAN (28-412): 3.45e-89: 299: 18.20
+	Sc
		376796 PABP_YEAST (217-320): 7.71e-21: 94.9: 21.15		IF4F1_YEAST (11-426): 1.36e-88: 292: 16.70
+	Dm
		247398 PABP_DROME (238-320): 4.52e-21: 95.6: 24.10		O61380_DROME (43-441): 1.12e-78: 269: 16.84
+	Sc
		376797 PABP_YEAST (217-320): 7.71e-21: 94.9: 21.15		IF4F2_YEAST (13-440): 6.93e-80: 268: 14.35
+	Dm
		597074 PABP_DROME (238-320): 4.52e-21: 95.6: 24.10		Q9VCH1_DROME (117-377): 5.52e-63: 224: 18.57