HitPredict

Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: PTN2 (P17706)
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)
Gene: PTPN2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27880917, 28675297, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 415
+	Hs
		1206093 MIB1_HUMAN (1-226): 1.24e-58: 200: 29.87		PTN22_HUMAN (5-382): 1.24e-128: 391: 27.48
+	Hs
		573970 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		PTN1_HUMAN (4-413): 1e-158: 455: 51.93
+	Hs
		577019 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		PTPRA_HUMAN (3-276): 1.17e-103: 326: 29.12
+	Hs
		161362 MYPT1_HUMAN (146-226): 1.06e-18: 85.9: 30.86		PTPRJ_HUMAN (4-307): 5.14e-125: 393: 31.73
+	Hs
		616983 POTEA_HUMAN (1-141): 3.45e-27: 109: 20.57		PTPRD_HUMAN (17-276): 6.69e-108: 351: 32.45
+	Hs
		796421 ANKH1_HUMAN (1-61): 4.98e-09: 57.7: 16.39		PTN9_HUMAN (4-277): 3.68e-121: 365: 37.11
+	Hs
		883516 RIPK4_HUMAN (10-224): 1.17e-53: 185: 26.39		PTPRK_HUMAN (18-279): 2.08e-62: 219: 23.72
+	Hs
		1069970 Q9H4D1_HUMAN (10-224): 1.95e-53: 184: 26.39		PTPRK_HUMAN (18-279): 2.08e-62: 219: 23.72
+	Hs
		640287 ANR50_HUMAN (20-222): 8.28e-53: 184: 23.65		PTN3_HUMAN (37-273): 1.6e-53: 193: 41.91
+	Hs
		640286 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		PTN3_HUMAN (37-273): 1.6e-53: 193: 41.91