Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: PRS6B (P43686)
26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (MB67-interacting protein) (MIP224) (Proteasome 26S subunit ATPase 4) (Tat-binding protein 7) (TBP-7)
Gene: PSMC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 17353931, 33961781, 11779854, 19412159, 19490896, 12525503, 25416956, 16189514, 28514442, 32296183, 35271311, 21988832, unassigned1304, 24338975
Identification Methods affinity chromatography technology, pull down, biochemical, two hybrid, two hybrid prey pooling approach, two hybrid array, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid, mammalian protein protein interaction trap and 1 others

more...

Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~Ank, AAA_lid_3~Ank_2
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 226
Hs

1 418
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024