HitPredict

Interactor 1: PSD10 (O75832)
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin) (p28(GANK))
Gene: PSMD10

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20628200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 226 Hs			1 193
+	Hs
		925204 ANK2_HUMAN (11-224): 2.93e-64: 217: 28.29		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		900423 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925238 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		950953 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		893947 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		915638 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		883465 RIPK4_HUMAN (10-224): 1.17e-53: 185: 26.39		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		900896 Q9H4D1_HUMAN (10-224): 1.95e-53: 184: 26.39		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		120412 ANK3_HUMAN (11-224): 5.98e-60: 205: 29.22		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		901042 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925723 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436568 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		951454 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		894580 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545696 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		892676 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		916068 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120709 KDIS_HUMAN (1-142): 3.7e-32: 125: 25.52		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		545454 POTEE_HUMAN (1-125): 1.17e-24: 103: 22.40		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		120683 RAI14_HUMAN (1-109): 2.71e-20: 90.8: 23.85		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98