HitPredict

Interactor 1: IDHC (O75874)
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDH1

Interactor 2: IDHC (O75874)
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDH1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.884

The method score is based on:

Property Details
Experiments 26280302, 19935646, 26436839, 21516116
Identification Methods x-ray crystallography, molecular sieving, two hybrid
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Iso_dh~Iso_dh
Common GO terms GO:0000287 - magnesium ion binding
GO:0004450 - isocitrate dehydrogenase (NADP+) activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 22 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 414
Hs

1 414
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024