HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23222715
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE~VHS
Common GO terms	GO:0005829 - cytosol GO:0031901 - early endosome membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 1425
+	Hs
		277083 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		ZFY16_HUMAN (1-1424): 0: 1145: 30.54
+	Hs
		241175 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		ZFY16_HUMAN (1-1424): 0: 1145: 30.54
+	Hs
		1045445 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		ZFY16_HUMAN (1-1424): 0: 1145: 30.54
+	Hs
		160062 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		ZFY16_HUMAN (1-1424): 0: 1145: 30.54
+	Hs
		159809 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Mm
		292346 STAM2_MOUSE (1-525): 3.68e-132: 395: 85.14		HGS_MOUSE (654-976): 1.93e-52: 200: 19.94
+	Hs
		160122 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Hs
		1045439 SPTN1_HUMAN (103-481): 2.5e-55: 202: 14.59		FGD5_HUMAN (151-872): 3.46e-92: 330: 14.82
+	Hs
		241169 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42
+	Hs
		159801 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Dm
		1280459 Q9XTL2_DROME (3-482): 1e-73: 248: 33.65		HRS_DROME (654-978): 7.91e-47: 183: 16.41
+	Hs
		160224 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Hs
		159808 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Hs
		160208 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Ce
		136435 STAM1_CAEEL (4-395): 5.28e-65: 219: 27.27		Q17796_CAEEL (653-978): 4.1e-46: 180: 13.83
+	Hs
		160223 GGA2_HUMAN (2-511): 3.8e-55: 197: 16.80		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Ce
		1089151 Q17796_CAEEL (5-156): 3.75e-46: 173: 28.95		Q17796_CAEEL (653-978): 4.1e-46: 180: 13.83
+	Hs
		159777 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55
+	Mm
		1307830 HGS_MOUSE (135-518): 6.07e-14: 76.7: 11.00		HGS_MOUSE (654-976): 1.93e-52: 200: 19.94
+	Hs
		159946 GRB2_HUMAN (207-262): 4.5e-12: 67.4: 52.63		HGS_HUMAN (654-976): 7.98e-53: 202: 19.55