HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 796
+	Hs
		385279 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		277074 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72
+	Hs
		277073 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37
+	Hs
		277003 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59
+	Hs
		277002 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		241132 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		1081556 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37
+	Hs
		608072 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59
+	Hs
		385689 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98
+	Hs
		276988 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RET_HUMAN (391-794): 3.5e-114: 374: 30.44
+	Hs
		277011 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36
+	Hs
		508257 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		608178 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59
+	Hs
		872470 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36