HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.974

Property	Details
Experiments	20504764, 28190767, 31699778, 31494268, 18626516, 38803224, 26601948, 27725184, 21121635, 22841719, 12750381
Identification Methods	pull down, unspecified method, x-ray crystallography, surface plasmon resonance
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 685
+	Hs
		476138 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475949 TM1L2_HUMAN (1-466): 2.13e-88: 282: 17.19		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		241137 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476541 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		272789 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		UBC_HUMAN (1-685): 0: 846: 100.00
+	Bt
		477668 Q58CQ6_BOVIN (2-422): 1.22e-59: 205: 13.66		UBC_BOVIN (1-613): 0: 753: 99.18
+	Sc
		477314 VPS27_YEAST (1-488): 4.18e-59: 208: 16.02		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	Hs
		277047 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		276992 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Mm
		292343 STAM2_MOUSE (1-525): 3.68e-132: 395: 85.14		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Ce
		136432 STAM1_CAEEL (4-395): 5.28e-65: 219: 27.27		UBIQ1_CAEEL (1-229): 5.97e-87: 292: 98.25
+	Hs
		924099 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476756 STAM1_MOUSE (1-513): 1.83e-114: 351: 53.96		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		78185 B5DF55_RAT (1-513): 1.4e-112: 346: 54.25		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		476811 TM1L2_MOUSE (1-466): 2.1e-87: 280: 17.79		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		292209 TOM1_MOUSE (1-465): 4.98e-83: 268: 17.10		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		241134 TOM1_HUMAN (1-444): 1.01e-80: 262: 17.68		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Mm
		476921 GGA1_MOUSE (2-516): 2.12e-64: 222: 14.61		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476884 GGA3_MOUSE (1-513): 7.9e-59: 209: 15.33		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		475230 GGA1_HUMAN (2-516): 8.21e-63: 218: 14.50		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70