HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 802
+	Hs
		277002 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR2_HUMAN (4-797): 0: 737: 56.44
+	Hs
		277004 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR3_HUMAN (5-799): 0: 712: 61.07
+	Hs
		276996 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		608072 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR4_HUMAN (13-802): 0: 750: 100.00
+	Hs
		601561 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR2_HUMAN (4-797): 0: 737: 56.44
+	Hs
		609455 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR3_HUMAN (5-799): 0: 712: 61.07
+	Hs
		508131 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		277011 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA3_HUMAN (4-778): 0: 595: 18.34
+	Hs
		277067 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA7_HUMAN (4-781): 0: 584: 19.90
+	Hs
		277037 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA4_HUMAN (4-776): 0: 582: 19.47
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (4-771): 0: 580: 18.81
+	Hs
		277010 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA2_HUMAN (4-789): 0: 573: 19.58
+	Hs
		277152 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA6_HUMAN (4-767): 0: 565: 19.93
+	Hs
		277012 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA8_HUMAN (4-763): 0: 549: 19.79
+	Hs
		277074 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK2_HUMAN (114-757): 9.58e-166: 502: 25.84
+	Hs
		277073 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24
+	Hs
		665303 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA2_HUMAN (4-789): 0: 573: 19.58
+	Hs
		276985 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		276988 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		RET_HUMAN (221-802): 2.33e-148: 465: 34.72
+	Hs
		385279 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53