HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 983
+	Hs
		277036 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA5_HUMAN (7-983): 0: 1202: 65.97
+	Hs
		277067 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA7_HUMAN (6-979): 0: 1198: 61.46
+	Hs
		277037 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA4_HUMAN (8-983): 0: 1164: 62.40
+	Hs
		277152 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA6_HUMAN (3-980): 0: 1146: 60.16
+	Hs
		872470 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA5_HUMAN (7-983): 0: 1202: 65.97
+	Hs
		277012 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA8_HUMAN (29-982): 0: 1099: 56.57
+	Hs
		277010 STAM2_HUMAN (1-525): 4.7e-141: 418: 100.00		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		665436 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		EPHA3_HUMAN (1-983): 0: 1248: 100.00
+	Hs
		665508 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA8_HUMAN (29-982): 0: 1099: 56.57
+	Hs
		872497 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		EPHA5_HUMAN (7-983): 0: 1202: 65.97
+	Hs
		665303 STAM1_HUMAN (1-510): 2.25e-111: 343: 54.88		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		665608 ITSN1_HUMAN (188-414): 1.91e-46: 176: 22.50		EPHB2_HUMAN (29-981): 0: 1167: 55.90
+	Hs
		159898 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA3_HUMAN (1-983): 0: 1248: 100.00
+	Hs
		159937 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA5_HUMAN (7-983): 0: 1202: 65.97
+	Hs
		159900 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHB2_HUMAN (29-981): 0: 1167: 55.90
+	Hs
		159899 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA8_HUMAN (29-982): 0: 1099: 56.57
+	Hs
		159897 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		EPHA2_HUMAN (27-983): 0: 1061: 50.47
+	Hs
		435783 GGA3_HUMAN (1-510): 1.35e-56: 203: 15.73		IGF1R_HUMAN (366-883): 1.6e-139: 453: 30.02
+	Hs
		159843 HGS_HUMAN (135-518): 7.87e-15: 79.4: 10.95		INSR_HUMAN (375-880): 6.57e-136: 444: 30.32
+	Hs
		272786 TM1L1_HUMAN (6-494): 3.07e-63: 215: 16.02		FYN_HUMAN (615-879): 1.08e-64: 229: 44.20