HitPredict

Interactor 1: CCNK (O75909)
Cyclin-K
Gene: CCNK

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 35013218
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0006974 - DNA damage response
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 580 Hs			1 454
+	Hs
		236674 CCNT1_HUMAN (14-396): 1.54e-70: 242: 22.25		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Mm
		348449 CCNT1_MOUSE (14-396): 2.42e-66: 231: 22.25		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Hs
		346280 CCNH_HUMAN (41-227): 5.93e-53: 185: 20.31		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		277470 CCNK_HUMAN (1-580): 3.11e-92: 296: 100.00		MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11
+	Hs
		236732 CCNT1_HUMAN (14-396): 1.54e-70: 242: 22.25		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67
+	Mm
		659357 CCNT1_MOUSE (14-396): 2.42e-66: 231: 22.25		MAX_MOUSE (354-454): 3.52e-25: 102: 32.67