HitPredict

Interactor 1: PRAF3 (O75915)
PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Cytoskeleton-related vitamin A-responsive protein) (Dermal papilla-derived protein 11) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (JM5) (Prenylated Rab acceptor protein 2) (Protein JWa) (Putative MAPK-activating protein PM27)
Gene: ARL6IP5

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22119785, 37931956
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 1104
+	Hs
		242282 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		48206 PRAF3_HUMAN (1-188): 9.94e-86: 252: 100.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		48197 PRAF2_HUMAN (2-175): 3.94e-69: 209: 45.40		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32