HitPredict

Interactor 1: PIAS2 (O75928)
E3 SUMO-protein ligase PIAS2 (EC 2.3.2.-) (Androgen receptor-interacting protein 3) (ARIP3) (DAB2-interacting protein) (DIP) (E3 SUMO-protein transferase PIAS2) (Msx-interacting zinc finger protein) (Miz1) (PIAS-NY protein) (Protein inhibitor of activated STAT x) (Protein inhibitor of activated STAT2)
Gene: PIAS2

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	21516116, 34079125
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 586
+	Hs
		277871 PIAS1_HUMAN (1-621): 0: 653: 54.10		K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82
+	Hs
		278203 PIAS2_HUMAN (1-621): 0: 811: 100.00		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		278222 PIAS2_HUMAN (1-621): 0: 811: 100.00		DESM_HUMAN (28-390): 1.04e-28: 121: 31.13
+	Hs
		278216 PIAS2_HUMAN (1-621): 0: 811: 100.00		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		278242 PIAS2_HUMAN (1-621): 0: 811: 100.00		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79
+	Hs
		277932 PIAS1_HUMAN (1-621): 0: 653: 54.10		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		277872 PIAS1_HUMAN (1-621): 0: 653: 54.10		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		277973 PIAS1_HUMAN (1-621): 0: 653: 54.10		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79
+	Hs
		360149 PIAS4_HUMAN (2-499): 1.7e-172: 502: 43.32		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		443652 PIAS4_HUMAN (2-499): 1.7e-172: 502: 43.32		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65