HitPredict

Interactor 1: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2

Interactor 2: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.50	0.588

Property	Details
Experiments	25416956, 33961781
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 225 Hs			1 431
+	Hs
		278357 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		KRT34_HUMAN (29-430): 8.36e-153: 440: 62.53
+	Hs
		278364 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		K2C75_HUMAN (2-414): 4.39e-87: 277: 24.88
+	Hs
		278401 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		K1C20_HUMAN (84-407): 2.24e-87: 274: 47.22
+	Hs
		278502 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		KRT35_HUMAN (2-427): 4.45e-87: 274: 59.35
+	Hs
		278358 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		KRT36_HUMAN (7-407): 2.14e-84: 267: 63.34
+	Hs
		278359 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		KRT37_HUMAN (1-429): 1.93e-75: 243: 48.25
+	Hs
		278452 SPF27_HUMAN (1-225): 9.37e-103: 298: 100.00		K1H1_HUMAN (48-425): 7.13e-75: 241: 63.23