HitPredict

Interactor 1: SPF27 (O75934)
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2) (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27)
Gene: BCAS2

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.701

The method score is based on:

Property	Details
Experiments	33961781, 22365833, 28515276, 34079125
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000375 - RNA splicing, via transesterification reactions GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing and 3 others more... GO:0016607 - nuclear speck GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	225
Hs

1	2335

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024