HitPredict

Interactor 1: DCTN3 (O75935)
Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22)
Gene: DCTN3

Interactor 2: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005869 - dynactin complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 186 Hs			1 376
+	Hs
		278590 DCTN3_HUMAN (1-186): 1.37e-111: 317: 100.00		ACTY_HUMAN (1-376): 0: 728: 90.43
+	Hs
		278600 DCTN3_HUMAN (1-186): 1.37e-111: 317: 100.00		ACTG_HUMAN (7-376): 0: 580: 52.67
+	Hs
		278598 DCTN3_HUMAN (1-186): 1.37e-111: 317: 100.00		ACTA_HUMAN (5-376): 0: 576: 52.66