HitPredict

Interactor 1: DNJC8 (O75937)
DnaJ homolog subfamily C member 8 (Splicing protein spf31)
Gene: DNAJC8

Interactor 2: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ, DnaJ~DnaJ_C
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0030544 - Hsp70 protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 253 Hs			1 340
+	Hs
		636379 DJB14_HUMAN (3-194): 7.16e-41: 146: 20.00		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		636431 DJB12_HUMAN (3-194): 1.86e-37: 136: 17.71		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		636366 DNJB7_HUMAN (56-190): 1.5e-37: 135: 19.26		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		636450 DJC16_HUMAN (46-174): 1.93e-35: 135: 20.93		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		636378 DNJB8_HUMAN (57-176): 3.03e-37: 132: 24.17		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		279277 DNJB5_HUMAN (56-169): 1.38e-35: 131: 18.42		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		257919 DNJB6_HUMAN (56-166): 6.85e-35: 128: 22.52		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		279354 DNJB5_HUMAN (56-169): 1.38e-35: 131: 18.42		DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60
+	Hs
		258234 DNJB6_HUMAN (56-166): 6.85e-35: 128: 22.52		DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60
+	Hs
		636420 DJC18_HUMAN (14-167): 2.92e-30: 117: 21.43		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		279350 DJB12_HUMAN (3-194): 1.86e-37: 136: 17.71		DNJB5_HUMAN (1-339): 3.31e-126: 366: 59.71
+	Hs
		681628 DJB12_HUMAN (3-194): 1.86e-37: 136: 17.71		DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77
+	Hs
		681537 DNJB3_HUMAN (56-194): 2.18e-38: 132: 19.42		DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77
+	Hs
		636382 DNJA4_HUMAN (59-129): 1.89e-11: 65.2: 33.80		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		1348098 DJB12_HUMAN (3-194): 1.86e-37: 136: 17.71		DJB11_HUMAN (2-338): 8.5e-105: 313: 32.26
+	Rn
		956849 DNJB9_RAT (54-186): 1e-34: 125: 20.30		DJB11_RAT (2-338): 1.28e-103: 309: 31.97
+	Hs
		681536 DNJA4_HUMAN (59-129): 1.89e-11: 65.2: 33.80		DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77
+	Hs
		1262155 DNJA4_HUMAN (59-129): 1.89e-11: 65.2: 33.80		DNJA4_HUMAN (5-339): 1.42e-115: 341: 32.49
+	Hs
		243524 DNJA4_HUMAN (59-129): 1.89e-11: 65.2: 33.80		DNJA2_HUMAN (2-339): 2.35e-115: 341: 33.24
+	Rn
		1164654 DJB11_RAT (59-118): 1.2e-11: 65.6: 35.00		DJB11_RAT (2-338): 1.28e-103: 309: 31.97