HitPredict

Interactor 1: RAD17 (O75943)
Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)
Gene: RAD17

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.658

The method score is based on:

Property Details
Experiments 10608806, 11418864, 18344987
Identification Methods unspecified method, affinity chromatography technology, in-gel kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 2 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 681
Hs

1 3056
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024