HitPredict

Interactor 1: DNJB5 (O75953)
DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)
Gene: DNAJB5

Interactor 2: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 348 Hs			1 457
+	Hs
		314005 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		BAG4_HUMAN (1-457): 0: 698: 100.00
+	Hs
		279359 DNJB5_HUMAN (1-348): 1.1e-147: 422: 100.00		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		324663 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12
+	Hs
		1354514 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		243236 DNJA2_HUMAN (2-347): 3.77e-127: 372: 34.37		BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12
+	Hs
		636441 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		681645 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		243665 DNJA2_HUMAN (2-347): 3.77e-127: 372: 34.37		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		1262169 DNJA4_HUMAN (5-346): 2.01e-125: 367: 32.85		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38
+	Hs
		1354287 DJB11_HUMAN (2-345): 1.94e-102: 307: 32.09		BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38