HitPredict

Interactor 1: DNJB5 (O75953)
DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)
Gene: DNAJB5

Interactor 2: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ, DnaJ~DnaJ_C
Common GO terms	GO:0005829 - cytosol GO:0006986 - response to unfolded protein GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 Hs			1 504
+	Hs
		279337 DNJB5_HUMAN (1-348): 1.1e-147: 422: 100.00		DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05
+	Hs
		1305132 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05
+	Hs
		636403 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05
+	Hs
		681574 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05
+	Hs
		279350 DNJB5_HUMAN (1-348): 1.1e-147: 422: 100.00		DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98
+	Hs
		279354 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13
+	Hs
		636378 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DNJB8_HUMAN (394-501): 4.62e-39: 143: 38.79
+	Hs
		279277 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13
+	Hs
		636431 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98
+	Hs
		636366 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DNJB7_HUMAN (394-501): 6.62e-35: 134: 38.94
+	Hs
		681628 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98
+	Hs
		279279 DNJB5_HUMAN (1-348): 1.1e-147: 422: 100.00		STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91
+	Hs
		681537 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		DNJB3_HUMAN (394-499): 9.96e-36: 131: 38.60
+	Hs
		636363 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		TMTC3_HUMAN (9-308): 2.55e-27: 118: 11.59
+	Hs
		685080 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91
+	Hs
		258234 DNJB4_HUMAN (1-348): 4.71e-137: 394: 61.78		DNJB6_HUMAN (394-459): 4.92e-14: 75.1: 56.06
+	Hs
		636254 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91
+	Hs
		174656 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03
+	Hs
		681339 DNJA1_HUMAN (5-346): 1.18e-127: 373: 35.16		STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91
+	Hs
		257919 DNJB1_HUMAN (1-346): 2.3e-130: 377: 59.71		DNJB6_HUMAN (394-459): 4.92e-14: 75.1: 56.06