HitPredict

Interactor 1: DNJB5 (O75953)
DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40)
Gene: DNAJB5

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33957083, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~DnaJ, DnaJ~DnaJ_C, DnaJ_C~DnaJ_C
Common GO terms GO:0005829 - cytosol
GO:0006986 - response to unfolded protein
GO:0051082 - unfolded protein binding
GO:0051085 - chaperone cofactor-dependent protein refolding
GO:0051087 - protein-folding chaperone binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 348
Hs

1 337
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Last updated: 15 Jul 2024