HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 17634952
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0034116 - positive regulation of heterotypic cell-cell adhesion GO:0045121 - membrane raft GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 509
+	Hs
		411719 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		LCK_HUMAN (1-509): 0: 661: 100.00
+	Hs
		279406 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		YES_HUMAN (26-507): 0: 581: 58.06
+	Hs
		522982 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		SRC_HUMAN (20-507): 0: 586: 55.00
+	Hs
		433759 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		LYN_HUMAN (1-509): 0: 582: 62.72
+	Hs
		433351 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		YES_HUMAN (26-507): 0: 581: 58.06
+	Hs
		433259 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		YES_HUMAN (26-507): 0: 581: 58.06