HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0016020 - membrane GO:0034976 - response to endoplasmic reticulum stress GO:0050821 - protein stabilization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 724
+	Hs
		129147 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		P85B_HUMAN (4-719): 6.38e-162: 486: 57.24
+	Hs
		64633 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHG32_HUMAN (14-613): 1.13e-61: 227: 13.99
+	Hs
		279587 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHG21_HUMAN (78-531): 1.19e-59: 221: 13.46
+	Hs
		279406 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		YES_HUMAN (568-724): 2.15e-31: 131: 20.61
+	Hs
		433351 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		YES_HUMAN (568-724): 2.15e-31: 131: 20.61
+	Hs
		1345232 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		RHG35_HUMAN (89-325): 8.1e-55: 206: 23.46
+	Hs
		433259 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		YES_HUMAN (568-724): 2.15e-31: 131: 20.61