HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 207
+	Hs
		279502 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99
+	Hs
		844922 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		914069 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99
+	Hs
		845477 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65
+	Hs
		279483 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Hs
		844518 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44
+	Dm
		284092 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		RAB7_DROME (1-207): 1.45e-95: 278: 76.33
+	Dm
		185509 Q9VWL0_DROME (2-229): 3.77e-22: 98.8: 16.23		O18332_DROME (2-206): 2.18e-83: 247: 32.68
+	Hs
		646145 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		646158 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73
+	Hs
		73285 B4E2V5_HUMAN (8-217): 2.07e-19: 88.8: 16.67		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		845337 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		844788 STML2_HUMAN (8-217): 5.68e-13: 71.8: 18.48		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44