HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 427 Hs			1 196
+	Hs
		279505 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		279500 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		279425 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		279407 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		279511 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		279495 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		279496 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		925277 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900464 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915676 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545373 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436299 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		950993 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		892369 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		894002 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		279430 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120248 FLOT1_HUMAN (1-427): 3.27e-145: 421: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		564528 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120435 FLOT2_HUMAN (4-419): 1.33e-139: 407: 47.61		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		120306 STOM_HUMAN (8-217): 8.04e-21: 93.8: 16.67		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98