HitPredict

Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0098794 - postsynapse GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 3097 Hs			1 768
+	Hs
		224713 KALRN_HUMAN (53-3092): 0: 1984: 59.19		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1041532 SPTN1_HUMAN (186-2165): 3.14e-107: 387: 12.77		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		963318 SPTB2_HUMAN (61-1626): 2.73e-78: 293: 12.52		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		862036 DAPK1_HUMAN (2789-3051): 1.17e-56: 220: 41.70		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042328 PKH4B_HUMAN (67-379): 6.12e-55: 215: 22.53		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1040969 SPTN1_HUMAN (186-2165): 3.14e-107: 387: 12.77		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		360643 SPTA1_HUMAN (220-1136): 4.04e-61: 236: 13.58		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1042847 MACF1_HUMAN (131-1022): 1.75e-09: 66.2: 9.48		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		963317 SPTB2_HUMAN (61-1626): 2.73e-78: 293: 12.52		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1043046 OBSCN_HUMAN (2268-3078): 2.27e-52: 208: 15.57		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		166484 MCF2L_HUMAN (998-1340): 4.6e-17: 90.7: 17.53		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Dm
		115202 M9PEF7_DROME (1295-1590): 6.3e-41: 169: 34.73		Q9V9R2_DROME (30-768): 0: 612: 24.52