HitPredict

Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30737378
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 3097 Hs			1 488
+	Mm
		1002016 TRIO_MOUSE (1-3097): 0: 2316: 95.75		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		57858 KALRN_MOUSE (51-3092): 0: 2008: 59.43		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Hs
		224729 KALRN_HUMAN (53-3092): 0: 1984: 59.19		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Mm
		561164 SPTN1_MOUSE (186-2165): 7.22e-106: 383: 12.24		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		82763 B9EKJ1_MOUSE (186-2165): 7.1e-105: 380: 12.32		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Hs
		974067 DYST_HUMAN (442-1367): 1.65e-16: 89.7: 10.25		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1045553 SPTN1_HUMAN (186-2165): 3.14e-107: 387: 12.77		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		963444 SPTB2_HUMAN (61-1626): 2.73e-78: 293: 12.52		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		164674 SPTN2_HUMAN (335-2015): 2.32e-70: 266: 12.03		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Mm
		1143708 SPTB2_MOUSE (61-642): 8.64e-21: 103: 11.15		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		1144985 MCF2L_MOUSE (675-1015): 4.1e-18: 94.2: 16.29		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Mm
		93293 E9PY12_MOUSE (675-1015): 5.66e-18: 93.8: 16.29		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89