HitPredict

Interactor 1: AKAP3 (O75969)
A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)
Gene: AKAP3

Interactor 2: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 853 Hs			1 381
+	Hs
		279999 AKAP3_HUMAN (1-853): 0: 1339: 100.00		KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53
+	Bt
		285138 AKAP3_BOVIN (1-853): 0: 1312: 74.65		KAP2_BOVIN (233-379): 1.96e-17: 85.1: 26.53
+	Hs
		498291 AKAP4_HUMAN (1-853): 0: 878: 31.86		KAP0_HUMAN (1-381): 1.4e-139: 404: 100.00
+	Hs
		533840 AKAP4_HUMAN (1-853): 0: 878: 31.86		KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53
+	Mm
		522356 SPKAP_MOUSE (690-851): 1.53e-44: 176: 23.67		KAP1_MOUSE (1-381): 2.29e-142: 410: 81.37
+	Hs
		498373 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP0_HUMAN (1-381): 1.4e-139: 404: 100.00
+	Hs
		679325 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP1_HUMAN (1-381): 1.35e-138: 401: 81.37
+	Hs
		679410 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP3_HUMAN (10-253): 4.9e-21: 95.9: 18.21
+	Hs
		533884 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP2_HUMAN (233-379): 1.21e-17: 85.5: 26.53