HitPredict

Interactor 1: AKAP3 (O75969)
A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)
Gene: AKAP3

Interactor 2: KAP2 (P13861)
cAMP-dependent protein kinase type II-alpha regulatory subunit
Gene: PRKAR2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	10319321, 11278869
Identification Methods	far western blotting, two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 853 Hs			1 404
+	Bt
		285138 AKAP3_BOVIN (1-853): 0: 1312: 74.65		KAP2_BOVIN (1-404): 1.94e-134: 392: 89.60
+	Hs
		279998 AKAP3_HUMAN (1-853): 0: 1339: 100.00		KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46
+	Hs
		533840 AKAP4_HUMAN (1-853): 0: 878: 31.86		KAP2_HUMAN (1-404): 6.63e-138: 401: 100.00
+	Hs
		498291 AKAP4_HUMAN (1-853): 0: 878: 31.86		KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46
+	Hs
		533884 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP2_HUMAN (1-404): 6.63e-138: 401: 100.00
+	Hs
		679410 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP3_HUMAN (4-402): 1.97e-123: 365: 64.34
+	Mm
		522356 SPKAP_MOUSE (690-851): 1.53e-44: 176: 23.67		KAP1_MOUSE (215-396): 7.61e-17: 83.3: 23.08
+	Hs
		498373 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP0_HUMAN (210-396): 6.96e-18: 86.4: 22.46
+	Hs
		679325 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		KAP1_HUMAN (215-396): 4.15e-17: 84: 22.53