HitPredict

Interactor 1: AKAP3 (O75969)
A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)
Gene: AKAP3

Interactor 2: ROP1B (Q9BZX4)
Ropporin-1B (Rhophilin-associated protein 1B)
Gene: ROPN1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	11278869
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007340 - acrosome reaction
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 853 Hs			1 212
+	Hs
		280006 AKAP3_HUMAN (1-853): 0: 1339: 100.00		ROP1A_HUMAN (1-212): 8.97e-139: 388: 95.76
+	Bt
		285142 AKAP3_BOVIN (1-853): 0: 1312: 74.65		ROP1_BOVIN (1-212): 6.82e-139: 388: 86.32
+	Hs
		280004 AKAP3_HUMAN (1-853): 0: 1339: 100.00		ROP1L_HUMAN (1-212): 7.58e-120: 341: 38.18
+	Bt
		285141 AKAP3_BOVIN (1-853): 0: 1312: 74.65		ROP1L_BOVIN (1-209): 3.9e-116: 331: 38.71
+	Hs
		1334814 AKA11_HUMAN (751-852): 8.08e-31: 133: 31.37		ROP1A_HUMAN (1-212): 8.97e-139: 388: 95.76