HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 806
+	Hs
		280015 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		KIT_HUMAN (19-794): 1.17e-165: 506: 24.62
+	Hs
		1072546 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		EPHA7_HUMAN (1-782): 0: 626: 21.22
+	Hs
		665393 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHA3_HUMAN (1-786): 0: 641: 20.68
+	Hs
		872669 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		EPHA4_HUMAN (1-781): 0: 622: 20.78
+	Hs
		1020163 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHA7_HUMAN (1-782): 0: 626: 21.22
+	Hs
		1072558 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		EPHA7_HUMAN (1-782): 0: 626: 21.22
+	Hs
		665589 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHB2_HUMAN (1-788): 0: 624: 19.15
+	Hs
		665633 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		EPHB2_HUMAN (1-788): 0: 624: 19.15
+	Hs
		872431 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHA5_HUMAN (1-777): 0: 622: 20.18
+	Hs
		872638 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHA4_HUMAN (1-781): 0: 622: 20.78
+	Mm
		872623 GRIP1_MOUSE (5-671): 6e-20: 99.8: 11.77		EPHB2_MOUSE (1-788): 0: 624: 19.03
+	Hs
		872678 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		EPHA4_HUMAN (1-781): 0: 622: 20.78
+	Hs
		665228 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		EPHA2_HUMAN (1-788): 0: 595: 21.50
+	Hs
		872410 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		EPHB3_HUMAN (1-786): 0: 585: 18.66
+	Hs
		1020166 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59
+	Hs
		1020168 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		NTRK2_HUMAN (159-756): 1.53e-161: 491: 25.51
+	Hs
		384744 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02
+	Hs
		434182 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		RET_HUMAN (453-801): 9.71e-98: 330: 48.63
+	Hs
		507970 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32
+	Hs
		608206 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31