HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: SSR3 (P32745)
Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SST3) (SSR-28)
Gene: SSTR3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	19071123
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 418
+	Rn
		223211 MPDZ_RAT (1-2070): 0: 1220: 84.50		SSR3_RAT (2-414): 1.15e-89: 279: 82.08
+	Mm
		677394 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		SSR3_MOUSE (3-414): 6.37e-88: 275: 81.80
+	Hs
		697555 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		SSR3_HUMAN (1-418): 3.95e-100: 306: 100.00
+	Hs
		697558 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		SSR3_HUMAN (1-418): 3.95e-100: 306: 100.00
+	Hs
		722923 NHRF3_HUMAN (928-1286): 8.93e-33: 137: 17.21		SSR5_HUMAN (1-370): 4.53e-88: 273: 52.56
+	Hs
		697557 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		SSR3_HUMAN (1-418): 3.95e-100: 306: 100.00
+	Hs
		429068 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB2_HUMAN (13-396): 2.35e-82: 260: 19.47
+	Mm
		578603 MAGI3_MOUSE (1157-2070): 2.4e-32: 140: 14.89		ADRB2_MOUSE (13-405): 5.24e-80: 254: 18.81
+	Hs
		697554 SCRIB_HUMAN (372-771): 2.46e-09: 65.1: 22.66		SSR3_HUMAN (1-418): 3.95e-100: 306: 100.00
+	Mm
		830268 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR4_MOUSE (3-333): 6.02e-77: 245: 46.04
+	Mm
		676813 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR1_MOUSE (37-332): 2.63e-75: 241: 50.84
+	Mm
		676818 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR2_MOUSE (7-370): 2.43e-82: 258: 45.53
+	Hs
		626691 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ADA1D_HUMAN (13-395): 3.92e-74: 243: 25.00
+	Rn
		495779 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		ADRB2_RAT (14-358): 6.39e-79: 251: 19.89
+	Rn
		677498 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		SSR4_RAT (2-333): 6.19e-78: 247: 46.13
+	Hs
		626682 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		ADA1D_HUMAN (13-395): 3.92e-74: 243: 25.00
+	Mm
		830267 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR4_MOUSE (3-333): 6.02e-77: 245: 46.04
+	Mm
		676812 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR1_MOUSE (37-332): 2.63e-75: 241: 50.84
+	Hs
		676802 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		SSR1_HUMAN (37-332): 6.49e-74: 237: 50.84
+	Hs
		626687 SCRIB_HUMAN (372-771): 2.46e-09: 65.1: 22.66		ADA1D_HUMAN (13-395): 3.92e-74: 243: 25.00