HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: CRFR1 (P34998)
Corticotropin-releasing factor receptor 1 (CRF-R-1) (CRF-R1) (CRFR-1) (Corticotropin-releasing hormone receptor 1) (CRH-R-1) (CRH-R1)
Gene: CRHR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23576434
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 415
+	Hs
		714736 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Hs
		714735 NHRF3_HUMAN (928-1286): 8.93e-33: 137: 17.21		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Hs
		714737 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Hs
		714738 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Hs
		714732 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Hs
		714733 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Mm
		722927 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		CRFR1_MOUSE (1-415): 1.03e-129: 381: 97.59
+	Hs
		714731 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		CRFR1_HUMAN (1-415): 8.88e-129: 379: 100.00
+	Mm
		722926 DLG3_MOUSE (1854-2062): 1.95e-16: 87.8: 24.65		CRFR1_MOUSE (1-415): 1.03e-129: 381: 97.59
+	Mm
		1143372 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		AGRL3_MOUSE (1-413): 4.15e-117: 375: 19.18
+	Mm
		1143371 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		AGRL1_MOUSE (6-413): 6.78e-113: 362: 18.20
+	Hs
		146758 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69
+	Hs
		819563 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		GIPR_HUMAN (17-413): 1.2e-93: 291: 26.49
+	Hs
		146761 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69
+	Hs
		146765 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69
+	Hs
		146762 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69
+	Mm
		1143383 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		AGRB3_MOUSE (4-392): 9.99e-81: 272: 19.48
+	Hs
		146753 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69
+	Mm
		1112552 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		AGRB1_MOUSE (3-377): 2.02e-80: 271: 19.95
+	Hs
		146752 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		AGRB1_HUMAN (3-377): 4.14e-79: 268: 19.69