HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0016327 - apicolateral plasma membrane GO:0045177 - apical part of cell
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 781
+	Hs
		717151 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717193 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717292 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717459 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		250615 LNX1_MOUSE (778-1435): 6.76e-22: 105: 11.45		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		717037 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Rn
		957063 GRIP1_RAT (5-262): 7.67e-20: 99.4: 15.04		CTNB1_RAT (1-781): 0: 625: 99.74
+	Mm
		970159 GRIP1_MOUSE (5-671): 6e-20: 99.8: 11.77		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Hs
		717039 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Mm
		970142 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		CTNB1_MOUSE (1-781): 0: 624: 99.87
+	Rn
		291512 MAGI2_RAT (1802-2068): 4.85e-11: 70.5: 14.13		CTNB1_RAT (1-781): 0: 625: 99.74
+	Hs
		717226 PARD3_HUMAN (1715-1936): 3.57e-10: 67.8: 28.88		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		717076 SCRIB_HUMAN (372-771): 2.46e-09: 65.1: 22.66		CTNB1_HUMAN (1-781): 0: 626: 100.00
+	Hs
		542388 PARD3_HUMAN (1715-1936): 3.57e-10: 67.8: 28.88		PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42
+	Ce
		86414 C1P635_CAEEL (50-391): 1.24e-37: 156: 18.79		HMP2_CAEEL (89-738): 1.07e-96: 316: 31.20
+	Hs
		119773 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ARVC_HUMAN (202-771): 5.66e-94: 316: 18.66
+	Ce
		86391 C1P633_CAEEL (5-226): 1.44e-18: 95.2: 19.73		H2L2I2_CAEEL (89-738): 6.48e-98: 321: 31.20
+	Ce
		88183 D3YT29_CAEEL (1794-2061): 6.46e-12: 73.2: 15.87		HMP2_CAEEL (89-738): 1.07e-96: 316: 31.20
+	Hs
		853663 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		IMA5_HUMAN (240-678): 2.52e-65: 228: 16.44
+	Hs
		134936 PARD3_HUMAN (1715-1936): 3.57e-10: 67.8: 28.88		IMA3_HUMAN (198-681): 7.05e-69: 237: 14.34