HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: DRD3 (P35462)
D(3) dopamine receptor (Dopamine D3 receptor)
Gene: DRD3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	14499480
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 400
+	Hs
		280021 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		5HT2A_HUMAN (5-400): 1.21e-61: 207: 25.48
+	Hs
		280029 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		5HT2B_HUMAN (5-400): 2.11e-61: 207: 23.40
+	Hs
		280022 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		5HT2C_HUMAN (49-400): 2.46e-58: 198: 27.22
+	Rn
		223210 MPDZ_RAT (1-2070): 0: 1220: 84.50		5HT2C_RAT (7-400): 4.8e-64: 213: 26.37
+	Hs
		441653 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB1_HUMAN (6-400): 5.72e-65: 216: 28.57
+	Hs
		429068 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB2_HUMAN (1-399): 2.19e-56: 192: 23.33
+	Mm
		578603 MAGI3_MOUSE (1157-2070): 2.4e-32: 140: 14.89		ADRB2_MOUSE (1-399): 2.51e-58: 197: 23.57
+	Hs
		441654 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		ADRB1_HUMAN (6-400): 5.72e-65: 216: 28.57
+	Hs
		626691 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ADA1D_HUMAN (14-394): 3.91e-70: 232: 30.47
+	Mm
		897201 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		DRD2_MOUSE (9-400): 1.46e-73: 238: 44.50
+	Hs
		441656 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		ADRB1_HUMAN (6-400): 5.72e-65: 216: 28.57
+	Hs
		626682 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		ADA1D_HUMAN (14-394): 3.91e-70: 232: 30.47
+	Hs
		783800 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		5HT2B_HUMAN (5-400): 2.11e-61: 207: 23.40
+	Hs
		441650 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		ADRB1_HUMAN (6-400): 5.72e-65: 216: 28.57
+	Rn
		574798 MAGI3_RAT (1312-1899): 5.54e-24: 113: 14.29		ADRB1_RAT (46-398): 5.46e-55: 189: 26.65
+	Hs
		656997 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		5HT2A_HUMAN (5-400): 1.21e-61: 207: 25.48
+	Hs
		600726 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		DRD1_HUMAN (46-400): 2.61e-63: 211: 28.38
+	Hs
		656994 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		5HT2A_HUMAN (5-400): 1.21e-61: 207: 25.48
+	Hs
		658227 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		5HT2C_HUMAN (49-400): 2.46e-58: 198: 27.22
+	Rn
		495779 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		ADRB2_RAT (1-399): 3.31e-57: 194: 23.57