HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: 5HT2B (P41595)
5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)
Gene: HTR2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11150294
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 481
+	Hs
		280021 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		5HT2A_HUMAN (17-481): 1.21e-77: 251: 40.21
+	Hs
		280022 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		5HT2C_HUMAN (74-464): 1.73e-70: 233: 42.68
+	Hs
		280028 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		DRD3_HUMAN (26-397): 2.84e-68: 225: 23.72
+	Rn
		223210 MPDZ_RAT (1-2070): 0: 1220: 84.50		5HT2C_RAT (35-464): 4.28e-77: 250: 41.61
+	Rn
		223211 MPDZ_RAT (1-2070): 0: 1220: 84.50		SSR3_RAT (10-481): 8.12e-63: 211: 15.74
+	Mm
		677394 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		SSR3_MOUSE (10-481): 1.48e-62: 211: 15.74
+	Hs
		783800 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		5HT2B_HUMAN (1-481): 1.42e-104: 322: 100.00
+	Hs
		441653 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB1_HUMAN (8-416): 4.69e-76: 248: 24.34
+	Hs
		429068 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB2_HUMAN (59-412): 2.72e-74: 241: 26.39
+	Mm
		578603 MAGI3_MOUSE (1157-2070): 2.4e-32: 140: 14.89		ADRB2_MOUSE (16-428): 4.35e-75: 243: 22.91
+	Hs
		441654 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		ADRB1_HUMAN (8-416): 4.69e-76: 248: 24.34
+	Hs
		441656 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		ADRB1_HUMAN (8-416): 4.69e-76: 248: 24.34
+	Hs
		626691 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ADA1D_HUMAN (57-391): 1.64e-74: 246: 24.48
+	Hs
		656997 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		5HT2A_HUMAN (17-481): 1.21e-77: 251: 40.21
+	Rn
		574798 MAGI3_RAT (1312-1899): 5.54e-24: 113: 14.29		ADRB1_RAT (71-416): 1.77e-68: 228: 26.42
+	Hs
		626682 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		ADA1D_HUMAN (57-391): 1.64e-74: 246: 24.48
+	Rn
		495779 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		ADRB2_RAT (57-417): 8.15e-74: 240: 25.07
+	Hs
		658227 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		5HT2C_HUMAN (74-464): 1.73e-70: 233: 42.68
+	Mm
		676813 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR1_MOUSE (28-450): 3.8e-64: 214: 18.20
+	Mm
		830268 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR4_MOUSE (11-400): 2.16e-63: 212: 18.72