HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	33961781, 24366813, 25796446, 30472188, 26933062, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 504
+	Hs
		280067 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		280050 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		280084 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		125592 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		1299602 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		1252467 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		1246432 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		808559 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808786 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		1271021 DLG3_HUMAN (666-872): 8.31e-18: 92.5: 28.23		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		808565 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Mm
		93273 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11
+	Hs
		1020213 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1246431 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1021560 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1199788 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		1300658 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		1246425 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		1220068 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		1021531 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27