HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: MTR1A (P48039)
Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor)
Gene: MTNR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	26514267
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 350
+	Hs
		429068 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB2_HUMAN (3-334): 5.8e-74: 236: 19.73
+	Mm
		578603 MAGI3_MOUSE (1157-2070): 2.4e-32: 140: 14.89		ADRB2_MOUSE (1-328): 8.1e-75: 238: 20.17
+	Hs
		722923 NHRF3_HUMAN (928-1286): 8.93e-33: 137: 17.21		SSR5_HUMAN (38-348): 5.09e-74: 234: 22.47
+	Hs
		441653 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		ADRB1_HUMAN (5-331): 2.16e-67: 220: 19.37
+	Rn
		574798 MAGI3_RAT (1312-1899): 5.54e-24: 113: 14.29		ADRB1_RAT (7-310): 2.09e-77: 246: 22.86
+	Mm
		830268 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR4_MOUSE (2-315): 3.34e-74: 235: 22.57
+	Hs
		815864 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		MTR1A_HUMAN (1-350): 1.56e-75: 238: 100.00
+	Hs
		441654 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		ADRB1_HUMAN (5-331): 2.16e-67: 220: 19.37
+	Mm
		676813 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		SSR1_MOUSE (13-314): 5.79e-69: 222: 20.78
+	Hs
		441656 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		ADRB1_HUMAN (5-331): 2.16e-67: 220: 19.37
+	Hs
		626691 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		ADA1D_HUMAN (7-306): 1.08e-69: 229: 21.28
+	Rn
		495779 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		ADRB2_RAT (1-328): 1.98e-74: 237: 19.89
+	Rn
		677498 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		SSR4_RAT (2-315): 2.06e-74: 236: 23.82
+	Mm
		830267 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR4_MOUSE (2-315): 3.34e-74: 235: 22.57
+	Hs
		626682 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		ADA1D_HUMAN (7-306): 1.08e-69: 229: 21.28
+	Mm
		676818 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR2_MOUSE (2-342): 4.14e-71: 227: 23.92
+	Mm
		676812 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SSR1_MOUSE (13-314): 5.79e-69: 222: 20.78
+	Hs
		676802 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		SSR1_HUMAN (13-314): 3.07e-67: 218: 20.78
+	Hs
		441650 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		ADRB1_HUMAN (5-331): 2.16e-67: 220: 19.37
+	Mm
		897201 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		DRD2_MOUSE (10-228): 6.88e-20: 92: 30.18