HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 247
+	Hs
		280040 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		904684 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982109 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Mm
		905355 LNX2_MOUSE (497-1086): 5.96e-25: 115: 15.05		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Hs
		905015 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		910195 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		250604 LNX1_MOUSE (778-1435): 6.76e-22: 105: 11.45		1433G_MOUSE (1-247): 3.15e-139: 392: 100.00
+	Hs
		905296 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982407 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		982652 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Ce
		86422 C1P635_CAEEL (50-391): 1.24e-37: 156: 18.79		14331_CAEEL (5-246): 2.81e-103: 301: 75.31
+	Mm
		926859 LNX2_MOUSE (497-1086): 5.96e-25: 115: 15.05		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		683644 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		683846 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Mm
		250606 LNX1_MOUSE (778-1435): 6.76e-22: 105: 11.45		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		927696 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647412 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		684204 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		684280 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		684417 GRIP1_HUMAN (5-671): 8.64e-22: 105: 12.20		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16