HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.718

Property	Details
Experiments	33961781, 34079125, 19615732, 16678097, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 1084
+	Mm
		1257405 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11
+	Hs
		280051 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		280087 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Mm
		1257408 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOL1_MOUSE (1-912): 1.67e-43: 173: 43.02
+	Mm
		1225208 MPDZ_MOUSE (1-2070): 0: 1213: 83.82		AMOL2_MOUSE (1-853): 8.67e-34: 142: 26.49
+	Hs
		1119035 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		1020172 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		1118998 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Mm
		1145448 PTN13_MOUSE (66-600): 1.52e-21: 105: 14.31		AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11
+	Hs
		1199783 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		1222264 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		1222248 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		61867 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		CC88B_HUMAN (39-1023): 2.68e-32: 138: 11.95
+	Hs
		1300698 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		148925 MAGI3_HUMAN (1157-2070): 7.64e-34: 145: 15.10		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		149188 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Mm
		1265177 LNX2_MOUSE (497-1086): 5.96e-25: 115: 15.05		RRBP1_MOUSE (149-759): 2.39e-10: 67.3: 9.98
+	Hs
		724926 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		149084 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		149079 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37