HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: LRFN4 (Q6PJG9)
Leucine-rich repeat and fibronectin type-III domain-containing protein 4
Gene: LRFN4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 22677168
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2070 Hs			1 635
+	Hs
		1020181 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		LRFN4_HUMAN (17-635): 1.88e-142: 430: 100.00
+	Hs
		1162228 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		LRFN4_HUMAN (17-635): 1.88e-142: 430: 100.00
+	Mm
		1143377 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		LRFN4_MOUSE (17-635): 1.54e-137: 417: 96.13
+	Hs
		1300681 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		LRFN1_HUMAN (17-565): 6.39e-104: 334: 50.81
+	Hs
		1020230 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		LRFN1_HUMAN (17-565): 6.39e-104: 334: 50.81
+	Mm
		1103493 DLG1_MOUSE (1619-1915): 5.55e-18: 92.8: 23.06		LRFN1_MOUSE (17-617): 6.09e-106: 339: 48.29
+	Mm
		1103492 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		LRFN1_MOUSE (17-617): 6.09e-106: 339: 48.29
+	Rn
		1115171 DLG1_RAT (4-229): 5.45e-18: 93.1: 17.62		LRFN2_RAT (17-591): 1.57e-98: 320: 52.69
+	Mm
		1193431 DLG1_MOUSE (1619-1915): 5.55e-18: 92.8: 23.06		LRFN2_MOUSE (17-591): 3.7e-98: 319: 52.69
+	Rn
		677783 DLG4_RAT (649-788): 2.68e-17: 90.5: 29.79		LRFN2_RAT (17-591): 1.57e-98: 320: 52.69
+	Mm
		1143368 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		LRFN2_MOUSE (17-591): 3.7e-98: 319: 52.69
+	Rn
		1115172 DLG3_RAT (1854-2062): 1.82e-16: 87.8: 24.65		LRFN2_RAT (17-591): 1.57e-98: 320: 52.69
+	Mm
		936183 DLG3_MOUSE (1854-2062): 1.95e-16: 87.8: 24.65		LRFN2_MOUSE (17-591): 3.7e-98: 319: 52.69
+	Mm
		1207544 DLG2_MOUSE (1629-2004): 2.56e-24: 113: 21.13		LRC4C_MOUSE (16-437): 2.82e-64: 225: 22.46
+	Mm
		1194737 LNX2_MOUSE (497-1086): 5.96e-25: 115: 15.05		AMGO1_MOUSE (16-369): 5.23e-57: 201: 24.17
+	Mm
		1143410 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		LRC4C_MOUSE (16-437): 2.82e-64: 225: 22.46
+	Hs
		1150769 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		VASN_HUMAN (15-516): 3.53e-60: 214: 22.09
+	Mm
		936185 DLG3_MOUSE (1854-2062): 1.95e-16: 87.8: 24.65		LRC4C_MOUSE (16-437): 2.82e-64: 225: 22.46
+	Mm
		471547 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		LRC4B_MOUSE (16-370): 4.11e-61: 218: 26.73
+	Hs
		1252489 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		LGR6_HUMAN (23-150): 2.55e-17: 88.4: 31.01