HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: KIBRA (Q8IX03)
Protein KIBRA (HBeAg-binding protein 3) (Kidney and brain protein) (KIBRA) (WW domain-containing protein 1)
Gene: WWC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28720576, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2070 Hs			1 1113
+	Hs
		280084 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		WWOX_HUMAN (5-113): 1.68e-31: 130: 29.46
+	Hs
		280032 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84
+	Hs
		1220068 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		KIBRA_HUMAN (1-1113): 0: 842: 100.00
+	Hs
		1021531 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		KIBRA_HUMAN (1-1113): 0: 842: 100.00
+	Hs
		1252491 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		SYTL2_HUMAN (189-810): 3.31e-99: 337: 15.75
+	Mm
		93273 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		E9PXB7_MOUSE (2-423): 1.73e-84: 294: 16.77
+	Mm
		802298 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		SYT1_MOUSE (661-794): 6.97e-47: 175: 26.87
+	Hs
		1299602 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09
+	Hs
		1271021 DLG3_HUMAN (666-872): 8.31e-18: 92.5: 28.23		NED4L_HUMAN (656-807): 2.04e-33: 141: 15.09
+	Mm
		1143429 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		NED4L_MOUSE (671-807): 7.62e-32: 136: 13.29
+	Hs
		1252467 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		WWP1_HUMAN (2-162): 9.09e-26: 117: 25.77
+	Hs
		1246432 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		WWP1_HUMAN (2-162): 9.09e-26: 117: 25.77
+	Hs
		1199788 MAGI2_HUMAN (73-1158): 8.22e-26: 119: 10.36		MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95
+	Hs
		1300658 MAGI1_HUMAN (1658-2069): 1.07e-23: 112: 16.64		MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95
+	Hs
		1246425 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		MAGI1_HUMAN (36-163): 3.73e-13: 76.5: 25.95
+	Hs
		808559 PTN13_HUMAN (5-702): 1.45e-20: 102: 11.67		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84
+	Hs
		125592 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		WWP2_HUMAN (35-303): 1.01e-10: 68.2: 16.36
+	Hs
		808786 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84
+	Hs
		808565 DLG1_HUMAN (1619-1915): 1.92e-18: 94.4: 23.06		YAP1_HUMAN (37-159): 1.07e-10: 67.6: 19.84