HitPredict

Interactor 1: MPDZ (O75970)
Multiple PDZ domain protein (Multi-PDZ domain protein 1)
Gene: MPDZ

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2070 Hs			1 245
+	Hs
		280063 MPDZ_HUMAN (1-2070): 0: 1287: 100.00		RN166_HUMAN (5-244): 4.23e-40: 140: 29.58
+	Hs
		1232886 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		RN138_HUMAN (1-245): 6.92e-57: 183: 100.00
+	Hs
		1246419 INADL_HUMAN (1922-2068): 4.04e-20: 100: 30.00		RN166_HUMAN (5-244): 4.23e-40: 140: 29.58
+	Hs
		1252569 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		585019 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		RO52_HUMAN (6-157): 6.92e-32: 123: 17.11
+	Hs
		1232922 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		PZRN3_HUMAN (1-164): 4.32e-25: 105: 18.79
+	Hs
		129581 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRAF5_HUMAN (8-245): 3.76e-30: 119: 15.06
+	Hs
		942403 DLG4_HUMAN (649-788): 3.1e-17: 90.2: 29.79		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		1024716 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69
+	Hs
		1115440 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRI60_HUMAN (4-184): 7.76e-29: 115: 15.30
+	Hs
		1149890 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRI68_HUMAN (4-235): 8.64e-29: 115: 14.94
+	Mm
		1112691 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		Q3UHJ1_MOUSE (6-204): 2.92e-32: 125: 17.00
+	Hs
		1252493 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRI39_HUMAN (9-186): 1.44e-28: 114: 17.22
+	Hs
		1252445 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		TRAF4_HUMAN (8-207): 1.85e-27: 111: 13.14
+	Hs
		1252551 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		PZRN3_HUMAN (1-164): 4.32e-25: 105: 18.79
+	Mm
		1141406 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		TRAF3_MOUSE (2-245): 1.13e-28: 115: 14.69
+	Hs
		1168357 LNX2_HUMAN (490-1086): 3.87e-26: 118: 13.72		PZRN4_HUMAN (1-105): 1.56e-18: 86.2: 23.59
+	Hs
		1168358 LNX1_HUMAN (782-1270): 1.19e-20: 101: 12.63		PZRN4_HUMAN (1-105): 1.56e-18: 86.2: 23.59
+	Mm
		193407 DLG4_MOUSE (649-788): 2.87e-17: 90.5: 29.79		RING1_MOUSE (2-74): 1.86e-21: 93.9: 27.40