HitPredict

Interactor 1: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Interactor 2: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.854

The method score is based on:

Property Details
Experiments 25416956, 26302480, 27519415
Identification Methods two hybrid, two hybrid array, molecular sieving, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Glutaredoxin~Glutaredoxin, Thioredoxin~Thioredoxin
Common GO terms GO:0002026 - regulation of the force of heart contraction
GO:0003723 - RNA binding
GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 335
Hs

1 335
+ At
+ Hs
+ Sc
+ Sc
+ At
+ Ec
+ Sc
+ Hs
+ Hs
+ Cr
+ Hs
+ Zm
+ Sp
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024